What is the "Topical (skin/hair)" protocol for GHK-Cu?

0.1% in cream or serum · 1-2× daily · 8-12 weeks

What is the "Systemic" protocol for GHK-Cu?

1-2 mg · Daily s.c. · 4-8 weeks

Dosing

GHK-Cu (the copper tripeptide) - dosing protocol

GHK-Cu in research protocols is applied topically (0.05-0.2% in cream/serum) or systemically under the skin (s.c. injection) 1-2 mg daily for 4-8 weeks. Systemic protocols are less studied than topical.

Route

Topical (cream/serum) or subcutaneous (s.c.)

Dose

Topical: 0.05-0.2%; systemic: 1-2 mg

Half-life

Short systemic (minutes); local retention longer

Storage

-20°C lyophilized, protected from light; reconstituted — 30 days at 2-8°C

Dosing regimens

Standard regimens from the literature. The choice depends on what you're trying to achieve.

Protocol

Topical (skin/hair)

Dose: 0.1% in cream or serum
Frequency: 1-2× daily
Duration: 8-12 weeks

Protocol

Systemic

Dose: 1-2 mg
Frequency: Daily s.c.
Duration: 4-8 weeks

Reconstitution

Reconstitute 100 mg vial with 5 mL bacteriostatic water → 20 mg/mL. 0.1 mL = 2 mg.

Reconstitution calculator

Side effects

GHK-Cu is well-tolerated topically. Systemic (s.c.) doses occasionally cause transient redness around the injection site and metallic taste. At high doses there is a theoretical risk of copper imbalance — multi-month protocols warrant periodic serum ceruloplasmin.

See full side-effect list

Encyclopedia

Full scientific profile for GHK-Cu

Calculator

What does this protocol cost per day?

Last reviewed: 6 May 2026by PeptidLabs Editorial

Dosing

GHK-Cu (the copper tripeptide) - dosing protocol

Route

Topical (cream/serum) or subcutaneous (s.c.)

Dose

Topical: 0.05-0.2%; systemic: 1-2 mg

Half-life

Short systemic (minutes); local retention longer

Storage

-20°C lyophilized, protected from light; reconstituted — 30 days at 2-8°C

Dosing regimens

Standard regimens from the literature. The choice depends on what you're trying to achieve.

Protocol

Topical (skin/hair)

Dose: 0.1% in cream or serum
Frequency: 1-2× daily
Duration: 8-12 weeks

Protocol

Systemic

Dose: 1-2 mg
Frequency: Daily s.c.
Duration: 4-8 weeks

Reconstitution

Reconstitute 100 mg vial with 5 mL bacteriostatic water → 20 mg/mL. 0.1 mL = 2 mg.

Reconstitution calculator

Side effects

See full side-effect list

Encyclopedia

Full scientific profile for GHK-Cu

Calculator

What does this protocol cost per day?

Last reviewed: 6 May 2026by PeptidLabs Editorial