Side effects

GHK-Cu (the copper tripeptide) - side effects

GHK-Cu is well-tolerated topically. Systemic (s.c.) doses occasionally cause transient redness around the injection site and metallic taste. At high doses there is a theoretical risk of copper imbalance — multi-month protocols warrant periodic serum ceruloplasmin.

Documented effects

Sorted by severity. Source cited when published.

Redness at injection site

mild·common

Metallic taste (systemic)

mild·uncommon

Skin pigmentation darkening with prolonged topical use

mild·rare

Dosing

GHK-Cu dosing protocol

Encyclopedia

Full scientific profile for GHK-Cu

Disclaimer: data is curated from research literature for in-vitro experiments. This is not medical advice.

Last reviewed: 6 May 2026by PeptidLabs Editorial