How common is "Arthralgia (joint pain)" with Tesamorelin?

common, mild - Falutz NEJM 2007.

Side effects

Tesamorelin (Egrifta) - side effects

The FDA-approved profile includes arthralgia (joint pain, 8%), peripheral edema (5%), paresthesia (numbness/tingling, 4%) — mostly from growth-hormone signaling. Glycemic monitoring, including HbA1c (long-term blood sugar), is recommended in clinical protocols.

Documented effects

Sorted by severity. Source cited when published.

Elevated blood glucose

moderate·uncommon

Arthralgia (joint pain)

mild·common·Falutz NEJM 2007

Peripheral edema

mild·common

Paresthesia

mild·uncommon

Injection-site reaction

mild·common

Contraindications

Active malignancy; pregnancy.

Dosing

Tesamorelin dosing protocol

Encyclopedia

Full scientific profile for Tesamorelin

Disclaimer: data is curated from research literature for in-vitro experiments. This is not medical advice.

Last reviewed: 6 May 2026by PeptidLabs Editorial

Side effects

Tesamorelin (Egrifta) - side effects

Documented effects

Sorted by severity. Source cited when published.

Elevated blood glucose

moderate·uncommon

Arthralgia (joint pain)

mild·common·Falutz NEJM 2007

Peripheral edema

mild·common

Paresthesia

mild·uncommon

Injection-site reaction

mild·common

Contraindications

Active malignancy; pregnancy.

Dosing

Tesamorelin dosing protocol

Encyclopedia

Full scientific profile for Tesamorelin

Disclaimer: data is curated from research literature for in-vitro experiments. This is not medical advice.

Last reviewed: 6 May 2026by PeptidLabs Editorial