sampleEnergy & metabolism
98%+ · 50mg · Tablets · MW: 286.11
Bulk discount
3+ pcs
€80.75
−5%
5+ pcs
€76.50
−10%
10+ pcs
€72.25
−15%
Discount is applied automatically at checkout.
Enter your email and we'll notify you when it's back:
Free shipping over €49
This product is sold strictly for in lab conditions (in vitro) research purposes. Not approved for human consumption.
Verified above 98%
98%+ verified — most batches reach 99%+
Included
Independent analysis from accredited laboratories
EU Shipping
3-7 days across the EU (Bulgaria — 1-2 days)
Secure Payment
Cash on delivery
5-Amino-1MQ Tablets 50 mg × 25
NNMT Inhibitor (Iodide Salt) | Longevity & Metabolism | Oral Research
In short
Selective NNMT inhibitor studied in cellular models for its modulation of energy metabolism and NAD+ levels.
Best sellers
Education
Related resources
5-Amino-1MQ is a small synthetic molecule that acts as a selective inhibitor of the NNMT enzyme. At the molecular level, it blocks the activity of this enzyme, preventing the depletion of crucial cellular resources and supporting the restoration of NAD+ levels. Researchers are studying the compound in laboratory settings (in vitro) and animal models to evaluate its effects on adipose tissue and cellular metabolism. 5-Amino-1MQ is strictly a research-grade chemical and is not an approved medication for human use.
Research reagent for laboratory use only. Not a medicine. For medical questions, consult a physician.
Scientific review
Written by
Калина Тодорова
Magister Pharmaciae, MSc Pharmacy
Reviewed by
Борис Маринов
MSc Biochemistry & Molecular Biology
Reviewed on
5-Amino-1MQ is a selective small-molecule inhibitor of NNMT, an enzyme implicated in adipose-tissue metabolic dysregulation. NNMT consumes the methyl group donor SAM and the NAD⁺ precursor nicotinamide, creating a metabolic sink that depletes cellular methylation capacity and NAD⁺ pools in tissues with high NNMT expression. Selective inhibition aims to restore both pools.
Selective NNMT inhibition (IC₅₀ ≈ 1.5 µM) Restores NAD⁺ salvage in NNMT-high tissues Preclinical adipose-tissue & muscle regeneration data Oral bioavailability established in animal models
5-Amino-1MQ competitively inhibits NNMT (IC₅₀ ≈ 1.5 µM), reducing 1-methylnicotinamide accumulation and restoring nicotinamide availability for NAD⁺ salvage. In white-adipose-tissue models the result is enhanced lipolysis, improved insulin sensitivity, and modulation of the methyl/NAD⁺ balance toward a phenotype associated with leaner metabolic profile.
Preclinical models of NNMT-mediated adipose dysregulation. Investigates whether restoring NAD⁺ salvage improves metabolic phenotype.
Limited human safety data. Iodide salt form contributes iodine load — protocols in iodine-replete subjects should monitor thyroid function over extended cycles. Long-term selective inhibition has not been characterized in human research; standard research-compound caution applies.
Compatibility
The pairings below come from research literature and established biohacker stacking patterns. Click a card for the full reasoning - when the partner is in our catalog you'll see a direct order link too.
This is a literature overview, not medical advice. Pairs not listed are not proven safe - they simply lack enough published data.
References
Links to peer-reviewed publications on PubMed, cited in the peptide's scientific profile.
NNMT regulates aged-muscle stem cell function
Mouse | Cell Metabolism 2019
Brown lab demonstrated that NNMT inhibition restores aged muscle stem-cell function through SAM/NAD⁺ balance restoration.
View the study
for longevity
for sexual health
No reviews yet. Be the first.
Share your experience with this peptide. We publish after a short moderation.
