sampleimmunosenescence
98%+ · 10mg · Lyophilized
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This product is sold strictly for in lab conditions (in vitro) research purposes. Not approved for human consumption.
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98%+ verified — most batches reach 99%+
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Thymalin
Thymic Peptide | Immune Modulator | Bioregulator
In short
Thymus peptide extract studied in gerontological models as a bioregulator of T-cell differentiation and immunity.
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Thymalin is a polypeptide complex originally isolated from the thymus gland that functions as a cellular bioregulator. At the molecular level, it interacts with immune system cells to regulate the balance of T- and B-lymphocytes and promote their differentiation. Researchers study this peptide in in vitro and animal models to observe its effects on cellular immunity and neuroendocrine homeostasis during physiological stress. This product is strictly for laboratory research purposes and is not an approved medication or therapeutic treatment for human use.
Research reagent for laboratory use only. Not a medicine. For medical questions, consult a physician.
Scientific review
Written by
Калина Тодорова
Magister Pharmaciae, MSc Pharmacy
Reviewed by
Борис Маринов
MSc Biochemistry & Molecular Biology
Reviewed on
Thymalin is a polypeptide complex originally isolated from the thymus gland. It functions as a bioregulator to modulate the immune system and support cellular function. The peptide influences the maturation and activity of T-lymphocytes. Lyophilized formulations require reconstitution with bacteriostatic water prior to subcutaneous or intramuscular injection.
Standardized thymus peptide extract (Khavinson) T-cell immunity restoration in aging populations Cytokine balance Th1/Th2/Th17/Treg 30+ years observational data
Thymalin interacts directly with the cellular mechanisms of the immune system to regulate the ratio of T-lymphocytes and B-lymphocytes. It stimulates phagocytosis and enhances cellular immunity by promoting T-cell differentiation. The peptide also demonstrates regulatory effects on the neuroendocrine-immune axis, supporting homeostasis during physiological stress.
Restores cellular immunity by normalizing T-cell and B-cell populations. Clinical applications often target immunodeficiency states and recovery from severe infections.
Dosing
The typical regimens you'll see in the published research - for reference when planning in vitro or in vivo experiments. Not medical advice.
Administer for 10 consecutive days.
Administer for 4 weeks, repeat cycle every 6-12 months.
Disclaimer
These are regimens discussed in the research literature, not medical advice. Consult a healthcare provider before use.
Timing
Administer in the morning or early afternoon to align with natural circadian immune fluctuations.
[Calculator]
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5.0marks
Standard insulin syringe 1 ml (100 marks)
Concentration
5.00mg/ml
Dose volume
0.050ml
U-100 units
5.0units
Doses per vial
40doses
Recommended needle
29G–30G / 1 ml insulin
Small volume — draw slowly; 30G works for finer precision
Cycle planner: vials for 12 weeks, cost, schedule
Opens full calculator
Results are reference values - for in vitro work. Verify against the published literature for the specific peptide.
[Step by step]
6 steps from a sealed vial to the injection. Plain language.
Peptide vial (10 mg), bacteriostatic water vial, 1 larger syringe (3-5 ml) for drawing water and 1 insulin (1 ml) for doses. Alcohol swabs for sanitizing the caps.
Wash your hands before starting.
Wipe the rubber cap of the water vial with an alcohol swab. Insert the needle, invert the vial and draw exactly 2 ml. Get the exact volume from the calculator.
Larger syringe = smaller error in volume.
Wipe the peptide vial cap. Tilt the vial 45° and release the water SLOWLY down the inner wall. Peptides are fragile — a direct stream onto the powder denatures them.
SLOWLY · DOWN THE WALL · NOT ONTO THE POWDER.
Hold the vial between both palms and swirl slowly. DO NOT shake or flip sharply — peptides break down under mechanical stress.
DON'T SHAKE. Like tea — not like a cocktail.
The powder should fully dissolve. The solution is clear, no visible particles. If cloudy or with sediment — discard (wrong water or bad batch).
Clear = OK. Cloudy = discard.
With the insulin syringe draw the exact marks from the calculator. Swab the skin (abdomen 5 cm around the navel, thigh, or buttock), pinch a fold, insert at 45-90° and inject slowly.
Rotate sites every injection to avoid lipohypertrophy.
Schedule
Administer in the morning or early afternoon to align with natural circadian immune fluctuations.
Thymalin is typically administered as a short, intensive course rather than continuous daily use. Clinical protocols often utilize intramuscular injection, though subcutaneous delivery is common in research settings.
Important
Thymalin is typically administered as a short, intensive course rather than continuous daily use. Clinical protocols often utilize intramuscular injection, though subcutaneous delivery is common in research settings.
Remove the plastic cap from the Thymalin vial and wipe the rubber stopper with an alcohol swab.
Draw 1 mL to 2 mL of bacteriostatic water into a sterile syringe.
Inject the water slowly into the vial, aiming the stream at the glass wall to prevent peptide damage.
Swirl the vial gently until the lyophilized powder is completely dissolved. Do not shake.
Inspect the solution to ensure it is clear and free of visible particles before use.
Generally well tolerated in clinical settings with a low incidence of adverse effects.
May cause mild irritation, redness, or swelling at the injection site.
Individuals with autoimmune disorders should exercise extreme caution as immune stimulation may exacerbate symptoms.
Long-term safety profile in healthy individuals using repeated cycles is not fully established.
Not recommended for pregnant or breastfeeding women due to lack of safety data.
References
Links to peer-reviewed publications on PubMed, cited in the peptide's scientific profile.
Peptides of pineal gland and thymus prolong human life
Human | 266 subjects | 6-8 years | Mortality rate
Researchers administered thymic and pineal peptides to elderly patients over several years. The treatment group demonstrated a significant reduction in acute respiratory diseases and lower mortality rates compared to the control group.
View the studyThymic bioregulators in the treatment of immunodeficiency
Human | Clinical review | Variable | Immune markers
Clinical evaluations of thymalin demonstrate its capacity to restore T-cell counts and enhance phagocytic activity in patients with secondary immunodeficiencies. The peptide effectively normalizes cellular immunity markers across various patient demographics.
Gerontological aspects of genome peptide regulation
Animal | Mice models | Lifespan | Cellular aging
Animal models receiving thymalin exhibited increased lifespan and preserved thymic function into advanced age. The peptide influenced gene expression related to immune function and cellular repair mechanisms.
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