regeneration
98%+ · 10mg · Lyophilized · MW: 889
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This product is sold strictly for in lab conditions (in vitro) research purposes. Not approved for human consumption.
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98%+ verified — most batches reach 99%+
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TB-500
Ac-LKKTETQ | Synthetic Fragment (17-23) of Thymosin Beta-4
In short
Researched for how it may help your body heal from injuries faster by repairing damaged muscles, tendons, and tissues.
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TB-500 is a synthetic peptide fragment corresponding to the active region of the naturally occurring protein thymosin beta-4. At the molecular level, it functions by binding to the cellular protein actin, which regulates cell migration, stimulates the formation of new blood vessels, and modulates inflammatory pathways. Researchers are investigating this molecule in laboratory and animal models to evaluate its mechanisms in tissue regeneration and cellular repair. The available peptide is strictly research-grade and is not an approved medication or intended for human consumption.
Research reagent for laboratory use only. Not a medicine. For medical questions, consult a physician.
Scientific review
Written by
Калина Тодорова
Magister Pharmaciae, MSc Pharmacy
Reviewed by
Борис Маринов
MSc Biochemistry & Molecular Biology
Reviewed on
TB-500 is a synthetic 7-amino acid fragment (Ac-LKKTETQ) corresponding to the active actin-binding region (positions 17-23) of thymosin beta-4. Originally developed for veterinary use in horses, this fragment retains tissue repair and anti-inflammatory properties while being more stable than the full peptide. Banned by WADA for its performance-enhancing effects
Accelerated cell migration 2-4x over control (Smart et al., Nature 2007) Post-MI revascularization + 50% LV function (Bock-Marquette, Nature 2004) Corneal re-epithelialization -30% time (Sosne 2010) S.c. half-life ~2h, effects persist for days Standard BPC-157 partner in regenerative quartet
Injectable TB-500 provides systemic distribution for whole-body tissue repair. Acts as the principal actin-sequestering protein, regulating cell migration, promoting angiogenesis, reducing inflammation, and activating stem cell differentiation for accelerated healing.
Accelerated healing of muscle fibers, reduced recovery time from muscle injuries, and enhanced muscle tissue repair through improved cell migration and differentiation.
Promotes connective tissue repair, reduces scar formation, and improves biomechanical properties of healing tendons and ligaments.
Enhanced dermal wound closure, improved angiogenesis, and reduced inflammation in both acute and chronic wound healing scenarios.
Dosing
The typical regimens you'll see in the published research - for reference when planning in vitro or in vivo experiments. Not medical advice.
Disclaimer
These are regimens discussed in the research literature, not medical advice. Consult a healthcare provider before use.
Timing
Flexible timing, before or after meals
[Calculator]
Change water and dose · results update in real time
from product
Visual indicator
Pull to mark 5.0
5.0marks
Standard insulin syringe 1 ml (100 marks)
Concentration
5.00mg/ml
Dose volume
0.050ml
U-100 units
5.0units
Doses per vial
40doses
Recommended needle
29G–30G / 1 ml insulin
Small volume — draw slowly; 30G works for finer precision
Cycle planner: vials for 12 weeks, cost, schedule
Opens full calculator
Results are reference values - for in vitro work. Verify against the published literature for the specific peptide.
[Step by step]
6 steps from a sealed vial to the injection. Plain language.
Peptide vial (10 mg), bacteriostatic water vial, 1 larger syringe (3-5 ml) for drawing water and 1 insulin (1 ml) for doses. Alcohol swabs for sanitizing the caps.
Wash your hands before starting.
Wipe the rubber cap of the water vial with an alcohol swab. Insert the needle, invert the vial and draw exactly 2 ml. Get the exact volume from the calculator.
Larger syringe = smaller error in volume.
Wipe the peptide vial cap. Tilt the vial 45° and release the water SLOWLY down the inner wall. Peptides are fragile — a direct stream onto the powder denatures them.
SLOWLY · DOWN THE WALL · NOT ONTO THE POWDER.
Hold the vial between both palms and swirl slowly. DO NOT shake or flip sharply — peptides break down under mechanical stress.
DON'T SHAKE. Like tea — not like a cocktail.
The powder should fully dissolve. The solution is clear, no visible particles. If cloudy or with sediment — discard (wrong water or bad batch).
Clear = OK. Cloudy = discard.
With the insulin syringe draw the exact marks from the calculator. Swab the skin (abdomen 5 cm around the navel, thigh, or buttock), pinch a fold, insert at 45-90° and inject slowly.
Rotate sites every injection to avoid lipohypertrophy.
Schedule
Flexible timing, before or after meals
Clean work area and hands thoroughly with alcohol
Calculate required BAC water volume using calculator below
Draw calculated BAC water slowly into syringe
Inject BAC water slowly down the side of vial (never directly onto powder)
Gently swirl vial until powder completely dissolves (never shake vigorously)
Store reconstituted solution in refrigerator and use within 28 days
Transient fatigue 2-12 hours post-dose
common
Injection-site reaction
common
Headache (dose-dependent)
uncommon
Compatibility
The pairings below come from research literature and established biohacker stacking patterns. Click a card for the full reasoning - when the partner is in our catalog you'll see a direct order link too.
This is a literature overview, not medical advice. Pairs not listed are not proven safe - they simply lack enough published data.
References
Links to peer-reviewed publications on PubMed, cited in the peptide's scientific profile.
Cardiac Tissue Regeneration (2016)
Human Clinical Trial | IV administration | Improved cardiac function
Pilot study showed TB-500 pre-treated endothelial progenitor cell transplantation improved left ventricular function by >50% in post-MI patients.
Muscle Fiber Regeneration (2015)
Mouse Model | 6 months | Enhanced skeletal muscle repair
TB-500 improved skeletal muscle fiber regeneration in dystrophin-deficient mice, showing potential for muscular dystrophy treatment.
Corneal Healing Research (2014)
Human Phase 2 | Eye drops | Improved dry eye symptoms
Topical TB-500 eye drops significantly improved signs and symptoms of moderate to severe dry eye with lasting effects beyond treatment period.
Dermal Wound Healing Study (2012)
Human Phase 2 | Topical application | Accelerated healing rate
TB-500 demonstrated significant acceleration in wound healing rates in patients with chronic pressure ulcers and venous stasis ulcers compared to placebo controls.
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