Research peptides · For laboratory and scientific research in vitro · Not medications · Not approved for consumption · Adults only (18+)
Glutathione (GSH)
In plain language
Glutathione (GSH) — the primary intracellular antioxidant. Studied for hepatic detoxification, mitochondrial redox balance and dermatological brightening.
For researchers
Glutathione (GSH) is a tripeptide with a unique γ-peptide bond between glutamate and cysteine (γ-Glu-Cys-Gly). It is the primary intracellular redox buffer in eukaryotes — its concentration in liver and erythrocyte cells is in the millimolar range. The thiol group (-SH) on the cysteine residue scavenges free radicals and recycles the oxidized forms of vitamins C and E. Clinical literature investigates GSH in three main directions: (1) hepatoprotection and Phase II detoxification, where GSH is a cofactor of glutathione-S-transferase; (2) mitochondrial redox balance — the GSH/GSSG ratio is a central biomarker for oxidative stress; (3) dermatological brightening via tyrosinase inhibition and shift from eumelanin toward pheomelanin. Sekhar and colleagues (Am J Clin Nutr 2011) document ~47% decline in erythrocyte GSH with age. In research protocols GSH is administered s.c., intravenously or intramuscularly. Precursors (NAC, glycine) are often used as supportive supplementation. Plasma half-life ~10 minutes; intracellular — hours. Storage: -20°C lyophilized, protected from light; reconstituted — 7 days at 2-8°C.
Scientific literature
Other peptides
Information about Glutathione is based on published scientific research and is intended for research purposes. Not medical advice.
Products related to this peptide are for in vitro laboratory research only. Not approved for human consumption.
