Oxytocin — neuropeptide of social bonding and reproduction
In short
9-amino acid neuropeptide studied in behavioral models for its role in social cognition and neuromodulation.
Overview
Oxytocin is a nine-amino-acid peptide hormone and neuropeptide naturally produced in the hypothalamus and released by the posterior pituitary. Known as the "love hormone" or "bonding hormone," it plays fundamental roles in social bonding, trust, empathy, sexual reproduction, childbirth, and lactation. Synthetic oxytocin (Pitocin/Syntocinon) is
Binds to oxytocin receptors (OXTR) on uterine smooth muscle cells, triggering calcium influx and myometrial contractions. Also stimulates prostaglandin release to enhance uterine sensitivity.
Molecular information
Research indications
Grouped by area. Each entry reflects a separate published hypothesis or clinical signal - not medical advice.
Kirsch et al. (J Neurosci 2005) - 24 IU intranasal reduces amygdala response to stress stimuli by 30-40%.
Окситоцинът обикновено се понася добре с минимални системни ефекти при изследователски дози. Честите странични ефекти включват леко главоболие, дразнене в носа и случайно гадене. Следете електролитите при продължителна употреба над 24 IU дневно. Може да повлияе временно на кръвното налягане. Не се препоръчва по време на бременност без медицинско наблюдение. Отбелязват се ефекти върху вътрешногруповите пристрастия. Консултирайте се с медицински специалист преди употреба, особено при психиатрични състояния. Спрете употребата при хиперстимулация на матката, аномалии в сърдечната честота на плода или признаци на руптура на матката. Други причини за спиране са тежка хипертония при майката, симптоми на водна интоксикация и тежка алергична реакция.
4 peer-reviewed sources
References
Links to peer-reviewed publications on PubMed, cited in the peptide's scientific profile.
Kirsch - fMRI
Clinical | 24 IU intranasally | single | Amygdala -30-40% activation
J Neurosci · 2005
View the studyInformation about Oxytocin is based on published scientific research and is intended for research purposes only. Not medical advice.
Products are for in vitro laboratory research only. Not approved for human consumption.
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